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Dark-field exam of fresh scrapings Benzathine penicillin 2. Asymptomatic infection from N. This asymptomatic infection makes up the main reservoir for gonococcal infection among homosexual men. Symptomatic infection appears 3 days to 2 weeks after exposure and is manifest by pruritis tenesmus, bloody discharge, mucopurulent discharge, or pain. Ulceration and erythema of the anus may be seen on inspection although more commonly this portion of the examination is unremarkable. The classic finding of anorectal gonococcal involvement is a thick purulent discharge that is expressed from the anal crypts in response to external anal pressure.I don't think you can get sick with an illness, but you can probably get some sort of infection (most likely in the vagina if you go from anal sex to vaginal) or you. If you're going to have anal sex and vaginal sex, here's the one thing you definitely have to do. An estimated 90% of men who have sex with men and as many as 5% to 10% of sexually active women engage in receptive anal intercourse...the end of the story look at the video above ↑ ↑ ↑